Home / The University / Faculties / Faculty of Chemistry and Pharmacy / Structures / Departments / Analytical Chemistry / Laboratories / Laboratory of Molecular Spectroscopy for Structural Analysis / Assist. Prof. Vyara Velcheva

   

CV

 

vyara

Vyara Velcheva

Email: ahvnv@chem.uni-sofia.bg

Phone: + 359 2 8161345

Sofia University „St. Kliment Ohridski”

Faculty of Chemistry and Pharmacy

1164 Sofia, 1 James Bourchier Blvd.

Education

  • Ph.D – Chemical Sciences (Analytical chemistry), Sofia University "St. Kliment Ohridski", 2023
  • M. Sc. – “Medicinal Chemistry”, Sofia University “St. Kliment Ohridski”, 2014
  • B. Sc. – “Computer Chemistry”, Sofia University “St. Kliment Ohridski”, 2012

Professional Experience

  • Assistant Professor (Analytical chemistry), Sofia University "St. Kliment Ohridski" (11. 2017 - present)
  • Assistant Professor (Analytical chemistry), Sofia University "St. Kliment Ohridski" (10.2015 – 07.2016)

Specializations

  • 3th Summer School of Bioinorganic Medicinal Chemistry, 2017, Cagliari, Sardegna, Italy, 28.08-02.09.2017
  • 3-weeks spetialization in Saarland University, Saarbrucken, Germany; 05-22.12.2016
  • International School on Introduction in the Rietveld structure refinement, Bulgarian Academy of Sciences, Sofia, Bulgaria, 28.09-03.10.2015
  • International School on Fundamental Chrystallography: Introduction on the international tables for Chrystallography, Sofia-Gyulechitsa, Bulgaria, 30.09-05.10.2013.
  • Second Balkan School on Fundamental Crystallography and Workshop on Magnetic Symmetry, Energy Institute, Istanbul Technical University Campus, Istanbul, Turkey, 13-19.07.15

Research Interests

  • coordination compounds, anticancer activity, IR-spectroscopy, UV-VIS-spectroscopy, NMR-spectroscopy, X-ray analysis

Publications

  • Velcheva, Vyara, Hegetschweiler, Kaspar and Gencheva, Galina. "Crystal structure of all-cis-2,4,6-trihydroxycyclohexane- 1,3,5-triaminium chloride sulfate, C6H18ClN3O7S" Zeitschrift für Kristallographie - New Crystal Structures, vol. 236, no. 6, 2021, pp. 1319-1321. https://doi.org/10.1515/ncrs-2021-0324
  • Velcheva, V.; Hegetschweiler, K.; Momekov, G.; Ivanova, S.; Ugrinov, A.; Morgenstern, B.; Gencheva, G. Platinum(IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic Drug Candidates. Pharmaceutics 2022, 14 (10). DOI: 10.3390/pharmaceutics14102057

Project Activity

  • Rational Design of New Metal-Based Antitumor Agents”, National Science Fund, Ministry of Education and Science, 2016-, Head of Project- assoc. prof. PhD G. Gencheva.
  • Study on the advantages of non-classical antitumor agents, based ot platinum complexes- New PtIV complexes with N,O-containing ligands, Scientific Research Fund, Sofia University “St. Kliment Ohridski”, 2016, Head of Project- assoc. prof. PhD G. Gencheva.

Teaching Activity

Period from - to Discipline Specialty
10.2015- 02.2016 Analytical Chemistry and Methods for Analysis Biology and Chemistry, Ecology and Environmental Protection
02.2016-05.2016 Analytical Chemistry I, II Biotechnology, Biology, Molecular Biology
02.2016-05.2016 Instrumental Methods for Analysis II Nuclear Chemistry, ECO chemistry, Chemistry
02.2018-present Instrumental Methods for Analysis II Nuclear Chemistry, ECO chemistry, Chemistry
02.2018-present Analytical Chemistry and Methods for Analysis Biotechnology, Biology, Molecular Biology
10.2018-present Analytical Chemistry I, II Computer Chemistry, ECO chemistry
10.2019- present Analytical Chemistry I, II Chemistry

Conferences

  1. Vyara Velcheva, Kaspar Hegetschweiler, Angel Ugrinov, Georgi Momekov and Galina Gencheva, Platinum(IV) complexes of the 1,3,5-triamino-1,3,5-trideoxy-cis-inositol- synthesis, structure and antiproliferative properties, Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology, Herceg Novi, Montenegro, 19 – 23.06.23, p. 135.
  2. Vyara N. Velcheva, Georgi T. Momekov, Angel G. Ugrinov, Nikola T. Burdjiev and Galina G. Gencheva, Studies on the Solution Behavior of Novel Platinum(IV) Complexes with a N,O- Chelating Ligand Designed as Potential Cytotoxic Agents, 2nd International Conference on Medicinal Chemistry and Drug Design, Renaissance Barcelona Fira Hotel, Barcelona, Spain, 19 - 20.08.19, p 42.
  3. V.Velcheva, G. Gencheva, A case study on the solution behavior of platinum(IV) complexes designed as potential antiproliferative agents, Chemistry Today for Tomorrow - A final conference in the framework of the project BG05M2OP001-2.009-0028 funded by operational program "Science and Education for Smart Growth, 01.02.19, p. 41
  4. V. Velcheva, G. Gencheva, 1, 3, 5-triamino-1, 3, 5-trideoxy-cis-inositol- characterization in solid state and in solution, VII National Crystallographic Symposium with International Participation, University of Chemical Technology and Metallurgy, Sofia, Bulgaria, 03 - 05.10.18, p. 94
  5. K. Hegetschweiler, V.Velcheva, A. Ugrinov, B. Morgenstern, G. Momekov, G. Gencheva, PtIV complexes of 1,3,5-triamin-1,3,5-trideoxy-cis-inositol – Structural Characterization and cytotoxic effects, Young Research Fellow Meeting, Faculty of Pharmacy, University of Paris-South, Paris, France, 08 - 10.02.17, p. 211
  6. K. Hegetschweiler, V.Velcheva, G. Gencheva, New PtIV complexes of N,O-containing ligand 1,3,5-triamino, 1,3,5-trideoxy-cis-inositol with potential antitumor activity, Sixth National Crystallographic Symposium with International Participation, Bulgarian Academy of sciences, Sofia, Bulgaria, 05 - 07.10.16, p. 49
  7. V. Velcheva, P. Gorolomova, G.Gencheva, Solid state structure of novel platinum complexes with potential antitumor properties and ligands, used for their formation, XV National Conference in Chemistry for students and PhD students, Faculty of Chemistry and Pharmacy, Sofia University “St. Kl. Ohridski”, Sofia, Bulgaria, 18 - 20.05.2016, стр. 17
  8. V. Velcheva, G. Gencheva, Study on the cytotoxic behavior of PT(IV) complexes with 1,3,5-triamino-1,3,5-trideoxy-cis-inositol, XIV National Conference in Chemistry for students and PhD students, Faculty of Chemistry and Pharmacy, Sofia University “St. Kl. Ohridski”, Sofia, Bulgaria, 20 - 22.05.2015, стр. 56
  9. K. Hegetschweiler, V. Velcheva, A. Ugrinov, G. Momekov, G. Gencheva, Synthesis, structural characterization and in-vitro antiproliferative effects of octahedral Platinum(IV) complexes with 1,3,5-triamino-1,3,5-trideoxy-cis-inositol, Fifth National Crystallographic Symposium with International Participation, University of chemical technology and metallurgy, Sofia, Bulgaria, 25 - 27.09.2014
  10. K. Hegetschweiler, V. Velcheva, St. Todorova, G. Momekov, G. Gencheva, PtIV complexes of 1,3,5-triamino-1,3,5-trideoxy-cis-inositol-Single-crystal structure and cytotoxic effects, Fourth National Crystallographic Symposium with International, University of chemical technology and metallurgy, Sofia, Bulgaria, 01 - 03.11.2012, p. 29
  11. P. Gorolomova, P. Shestakova, St. Todorova, V. Velcheva, G. Gencheva, Platinum(IV) complexes of 2,2’-dipyridylketone and its gem-diol form – Experimental and Theoretical NMR Study on Complex-Formation and Solution Structures, 14th Central and Eastern European NMR Symposium & Bruker Users’ Meeting, Golden Sands, Bulgaria, 16 - 19.09.2012, p. 78