phone: (+359 2) 81 67 293
e-mail: k_shishkova@biofac.uni-sofia.bg
Role: assistant professor
Laboratory of Virology, Faculty of Biology
Website: https://www.researchgate.net/profile/Kalina-Shishkova
Name: Kalina Avgust Shishkova, Ph.D.
Date and Place of Birth: 10.10.1970, Sofia, Bulgaria
Address: University of Sofia "St. Kl. Ohridski", 8 D. Tzankov blvd., Sofia 1164, Bulgaria
E-mail: k_shishkova@biofac.uni-sofia.bg; k_kostova1@abv.bg
Tel: +359-2-8167293
Education and Training
- Sofia University, Faculty of Biology, MSc in Virology, 1997
- Institute of Microbiology, Bulgarian Academy of Sciences, microbiologist, 1997- 2002
- Sofia University, Faculty of Biology, Ph.D. 2014
Kalina Shishkova is a university lecturer at Sofia University "St. Kliment Ohridski" - Faculty of Biology. He teaches molecular virology. In the master's degree, he lectures on antiviral immunity and bacteriophages and lysogeny. Her practical and teaching activities are related to the development of techniques for the isolation, cultivation and proof of infectivity of viruses. Her main research activity is aimed at screening substances of natural and synthetic origin for antiviral action. Another area of her interest is molecular screening and phylogenetic analysis of viruses newly isolated in Bulgaria. Participated in the first study that proved the prevalence of TTV among certain groups in the Bulgarian population.
Develops an adapted nested PCR system suitable and efficient for large-scale screening studies. One of the rapidly developing directions in plasma technologies, the so-called plasma medicine, is also of interest to her. Plasma medicine can be broadly defined as the application of plasma discharges for medical purposes. She was involved in determining the survival of virus-infected cells treated with low-temperature non-equilibrium gas-discharge plasma-activated nutrient medium, as well as in determining the type and amount of reactive oxygen species (ROS) produced under the influence of low-temperature non-equilibrium gas-discharge plasma. This research activity allowed her to acquire a thorough knowledge of most procedures in the purification of viruses, their adaptation to different cell cultures, the effects of virus-infected cells by various substances and physicochemical factors. All of these activities have resulted in publications in peer-reviewed journals.