Home / The University / Faculties / Faculty of Biology / Structures / Departments / Biochemistry / Lecturers / Assoc. Prof. Denitsa Teofanova, PhD

   

Phone: +359 2 8167 337
e-mail: teofanova@biofac.uni-sofia.bg

Address

Sofia University "St. Kliment Ohridski "., Faculty of Biology, Sofia 1164, 8 „Dragan Tsankov” Str.
Laboratory № 216;

Visiting hours: Monday and Wednesday from 10 to 12 h

Recent position Assistant Professor in Biological Sciences (Biochemistry)
Main activities and responsibilities

Assistant Professor – practice in „Biochemistry”.

Assistant Professor – practice in „Biocatalysis

 

Academic experience

 

2005 – 2006 – Molecular Biologist – IEPP – BAS.
2007 – 2011 – PhD Student – IEPP – BAS.

April. 2010 – September. 2010 – Researcher – IEPP – BAS.

September. 2010- now (second employment) – Assistant Professor – IBER – BAS.

2013 – 2014 – Part-time Assistant Professor in Department of "Biochemistry", Faculty of Biology, Sofia University "St. Kliment Ohridski ".
2014 – now - Assistant Professor in Department of "Biochemistry", Faculty of Biology, Sofia University "St. Kliment Ohridski

Education, academic degrees and titles

2004 – Bachelor degree in Molecular Biology - higher education, Faculty of Biology, Sofia University "St. Kliment Ohridski ".

2006 – Master degree in Molecular Biology – Genetics - higher education, Faculty of Biology, Sofia University "St. Kliment Ohridski ".

2011 – PhD in „Biochemistry” – IEMPAM- BAS.

National and international grants  

 

 

Project NSF Т 02/160. "Structural biology and specificity of DNA G-qudruplex ligand interactions". Head of the research team - Assoc. Prof. Boris Shivachev (IMC-BAS), Head from IBER-BAS - Assoc. Prof. Georgi Radoslavov.

Project . 543865-TEMPUS-1-2013-1-EG-TEMPUS-JPCR (2014-2017). Establishment of a common master's program in biotechnology with a focus on agriculture, environment and pharmacology. Head - Prof. Vlada Peneva (IBER-BAS).

Project „Young scientists” – YSP 02/23. 2010-2013. "Application of genetic polymorphism of milk proteins for selection and breeding of dairy cows in Bulgaria". Head – Assistant Prof. Petar Hristov, PhD.

European Social Fund Project; Operational Programme "Human Resources Development". 2007-2013. "Initiatives for attraction, promotion and enhancement of the quality of young scientific potential research in priority areas of medical and biological sciences".

Project "International cooperation" BAS / RAS. 2007-2010. "Investigation of host-parasite relationships of some of the most pathogenic helminths in animals and plants." Heads - Prof. Ilia Bankov and Acad. Sergey Oganesovich Movsesyan.

Joint Research Project. DFG-BASc. 2007-2009. „Comparative investigation of lipid binding proteins of parasitic nematodes from the genus Trichinella". Head – Prof. Ilia Bankov and Prof. Eva Liebau

Sixth Framework Programme, priority 5 Food Quality and Safety – DELIVER. 2006-2008 (FOOD-CT-200X-023025), „Design of Effective and sustainable control strategies for LIVER fluke in Europe". Head – Prof. Ilia Bankov

Additional qualification

Specialized course: „Parasitology and helmintology” – 2007г

Specialized course: „Genomics” – 2008г

Specialized course: „Molecular genetic studies and their application in practice” – 2009-2010г

Specialized course: „Modern electron microscopy techniques” – 2010г

Specialized course: „Molecular taxonomy, phylogeny and ecology” – 2010г

Specialized course: „Replication, transcription, translation, cell division – morphological aspect” – 2010г

Specializations

2009 - Germany, Münster, Institute of Zoophysiology, Molecular Physiology

2008 - Britain, Exeter, Institute of Biocatalysis

2008 - Northern Ireland, Belfast, Queen’s University

2007 - Germany, Münster, Institute of Zoophysiology, Molecular Physiology

Organisational skills and competences

Organization and equipment of scientific and research laboratories for PhD and graduate students.

Coordination and education of students in undergraduate and graduate programs during the development and defense of their theses.

Scientific publications  

 

 

 

 

 

1. Hristov P., Teofanova D., Neov B., Shivachev B., Radoslavov G. 2014. Mitochondrial diversity in autochthonous cattle breeds from the Balkan Peninsula. Czech Journal of Animal Science. ISSN 1212-1819. IF 0.871 – in press.

2. Hristov P., Teofanova D., Neov B., Radoslavov G. 2014. Haplotype diversity in autochthonous Balkan cattle breeds. Animal Genetics. Brief note. ISSN: 1365-2052. IF 2.21 – in press.

3. Hristov P., Teofanova D., Neov B., Zagorchev L., Radoslavov G. 2014. Population structure of two native Bulgarian cattle breeds with regard to CSN3 and CSN1S1 gene polymorphism. Bulg. J. Vet. Med. 17 (1): 18-24. ISSN 1311-1477. http://tru.uni-sz.bg/bjvm/bjvm.htm.

4. Walker S.M., Demiaszkiewicz A.W., Kozak M., Wedrychowicz H., Teofanova D., Prodohl P., Brennan G., Fairweather I., Hoey E.M., Trudgett A. 2013. Mitochondrial DNA haplotype analysis of liver fluke in bison from Bialowieza Primaeval Forest indicates domestic cattle as the likely source of infection. Vet Parasitol. 191(1-2):161-4. doi: 10.1016/j.vetpar.2012.08.002. ISSN: 0304-4017, IF 2.381

5. Zagorchev L., Dimitrova M., Odjakova M., Teofanova D., Hristov P. 2013. Electrophoretic characterization of milk proteins from Bulgarian Rhodopean cattle. Bulg. J. Agric. Sci. 19 (2), 197–200. ISSN 1310-0351, IF 0.189

6. Neov B., Teofanova D., Zagorchev L., Radoslavov G., Hristov P. 2013. Milk protein polymorphism in Bulgrian Grey cattle population. Bulg. J. Agric. Sci., 19 (2), 194–196, ISSN 1310-0351, IF 0.189

7. Hristov P., Teofanova D., Mehandzhiyski I., Zagorchev L., Radoslavov G. 2013 Significance of milk protein genes polymorphism for Bulgarian Rhodopean cattle: comparative studies. Biotechnol. & Biotechnol. EQ., 27 (2), 3659–3664. DOI: 10.5504/bbeq.2012.0132, ISSN 1310-2818, IF 0.622

8. Hristov P., Teofanova D., Mehandzhiyski I., Zagorchev L., Radoslavov G. 2012. Application of Milk Proteins Genetic Polymorphism for Selection and Breeding of Dairy Cows in Bulgaria, Chapter in “Milk Production - Advanced Genetic Traits, Cellular Mechanism, Animal Management and Health”, Narongsak Chaiyabutr (Ed.), ISBN: 978-953-51-0766-8, InTech, Available from: http://www.intechopen.com/books/milk-production-advanced-genetic-traits-cellular-mechanism-animal-management-and-health/application-of-milk-proteins-genetic-polymorphism-for-selection-and-breeding-of-dairy-cows-in-bulgar.

9. Teofanova D., Hristov P., Yoveva A., Radoslavov G. 2012. Issues associated with genetic diversity studies of the Liver Fluke, Fasciola heptica (Platyhelminthes, Digenea, Fasciolidae). Chapter in “Genetic Diversity / Book 4”. InTech Open Access Publisher. Prof. Mahmut Caliskan (Ed.), InTech, Available from: http://www.intechopen.com/books/genetic-diversity-in microorganisms/issues-associated-with-genetic-diversity-studies-of-the-liver-fluke-fasciola-heptica-platyhelminthes.

10. Teofanova D., Hristov P., Yoveva A., Radoslavov G. 2012. Native and recombinant fatty acid binding protein 3 from Fasciola hepatica as a potential antigen. Biotechnol. & Biotechnol. EQ. 26(1), 60-64. DOI: 10.5504/50YRTIMB.2011.0011. IF: 0.760

11. Hristov P., Teofanova D., Mehandzhiyski I., Yoveva A., Radoslavov G. 2012. Genotyping of endemic for Rhodopy mountain Shorthorn Rhodopean cow breed. Biotechnol. & Biotechnol. EQ. 26(1), 12-15. DOI: 10.5504/50YRTIMB.2011.0003. IF: 0.760

12. Teofanova D., Radoslavov G., Mehandzhiyski I., Yoveva А., Zagorchev L., Hristov P. 2011. Selection and breeding of Bulgarian Rhodopean cattle with respect to milk proteins polymorphism. Analele IBNA. 27, 15-25

13. Teofanova D., Hristov P., Yoveva A., Radoslavov G. 2011. Application of mitochondrial DNA as a molecule marker for definition of genetic structure of liver fluke (Fasciola hepatica) populations. Anniversary Scientific Session “110 years NDSRVMI”. 8-9 November. Sofia. Bulgaria. 167-172.

14. Hristov P., Teofanova D., Mehandzhiyski I., Zagorchev L., Radoslavov G. 2011. Effect of genetic polymorphism of αS1- casein gene on qualitative and quantitative bovine milk traits. Anniversary Scientific Session “110 years NDSRVMI”. 8-9 November. Sofia. Bulgaria. 249-253.

15. Hristov P., Teofanova D., Mehandzhiyski I., Yoveva A., Radoslavov G. 2011. Selection of diary cows with respect to kappa-casein gene polymorphism. Journal of Mountain Agriculture on the Balkans. 14 (4), 667-677.

16. Kantzoura V., Kouam M.K., Feidas H., Teofanova D., Theodoropoulos G. 2011. Geographic distribution modelling for ruminant liver flukes (Fasciola hepatica) in South-eastern Europe. International Journal for Parasitology. 41, 747-753. IF: 3,819.

17. Hristov P., Teofanova D., Radoslavov G. 2011. Effects of genetic variants of milk protein genes on milk composition and milk yield in cows of the Bulgarian black pied cattle. 2011. Comptes rendus de l'Académie bulgare des Sciences. 64 (1), 75-80. ISSN 1310-1331. IF: 0,204

18. Teofanova D., Kantzoura V., Walker S., Radoslavov G., Hristov P., Theodoropoulos G., Bankov I., Trudgett A. 2011. Genetic diversity of liver flukes (Fasciola hepatica) from Eastern Europe. Infection, Genetics and Evolution. 11, 109-115. IF: 3,223. doi:10.1016/j.meegid.2010.10.002.

19. Radoslavov G., Jordanova R., Teofanova D., Georgieva K., Hristov P., Salomone-Stagni M., Liebau E., Bankov I. 2010. A novel secretory poly-cysteine and histidine-tailed metalloprotein (Ts-PCHTP) from Trichinella spiralis (Nematoda) PLoS ONE 5(10): e13343. IF: 3,223. doi:10.1371/journal.pone.0013343.

20. Hristov P., Teofanova D., Radoslavov G. 2010. Usage genetic polymorphism of milk proteins for selection and breeding of dairy cattle in Bulgaria. NOVOSTI-BAS. 2 (78), 3-4. (Христов П., Теофанова Д., Радославов Г. 2010. Използване на генетичния полиморфизъм на млечните протеини при селекцията и развъждането на млечните породи говеда в Р. България. НОВОСТИ-БАН. 2 (78), 3-4.)

21. Zlatarev S., Hristov P., Teofanova D., Radoslavov G. 2008. The impact of genetic polymorphism of kappa-casein and beta-lactoglobulin loci on milk production traits in cows of the Bulgarian Rhodopean cattle. Comptes Rendus de l`Academie Bulgare des Sciences. 61 (12), 1577-1582. IF: 0,204. ISSN: 13101331.

22. Hristov P., Teofanova D., Zlatarev S. 2008. Genetic polymorphism of the principal milk proteins in the species Bos taurus. Diffusion and influence of the genetic variants with the quantitative and qualitative milk traits. J. Anim. Sci. 3, 227-236.

23. Radoslavov G., Teofanova D., Bankov I. 2008. Biodiversity and ecology of parasites of earth and water biocenose. Proceedings international scientific conference Acad. Scrjabin. Moscow. 9-11 2008. 305-309.

Participation in national and international scientific events  

 

 

 

 

 

  1. Hristov P., Teofanova D., Radoslavov G. 2014. Genetic structure of autochthonous Busha cattle population from Bulgaria. Third international scientific conference "State and development prospects of genetic resources in livestock " Borovets, Bulgaria 26-27 November 2014.
  2. Zagorchev L., Karakostova A., Teofanova D., Odjakova M. 2014. Extracellular chitinases in different stages of somatic embryogenesis in salt treated cultures of Dactylis glomerata L.The First National Conference on Biotechnology. Sofia, Bulgaria. 17th-18th October, 2014.
  3. Hristov P., Teofanova D., Neov B., Zagorchev L., Radoslavov G. 2013. Genetic polymorphism of milk proteins in Bulgarian native cow breeds. International Scientific Conference 90 years Faculty of Veterinary Medicine in Bulgaria, Stara Zagora, 30-31 May 2013.
  4. Zagorchev L., Dimitrova M., Odjakova M., Teofanova D., Hristov P. 2012. Electrophoretic characterization of milk proteins from Bulgarian Rhodopean cattle – application in selection and biodiversity preservation. Youth Scientific Conference " Kliment days " 22-23 November 2012 .
  5. Neov B., Teofanova D., Zarorchev L., Radoslavov G., Hristov P. 2012. Milk protein polymorphism in Bulgarian grey cattle population. Youth Scientific Conference " Kliment days " 22-23 November 2012 .
  6. Neov B. Teofanova D. Radoslavov G. Hristov P. 2012. Use of gene specific molecular markers in genotyping of endemic for mountain areas animals with important economic significance. 5th Spring Seminar of PhD students and young scientists from BAS "Interdisciplinary Chemistry", 20 - 22 April 2012 Sofia.
  7. Teofanova D., Hristov P., Yoveva A., Radoslavov G. 2011. Application of mitochondrial DNA as a molecule marker for definition of genetic structure of liver fluke (Fasciola hepatica) populations. Anniversary Scientific Session “110 years NDSRVMI”. 8-9 November. Sofia. Bulgaria.
  8. Hristov P., Teofanova D., Mehandzhiyski I., Zagorchev L., Radoslavov G. 2011. Effect of genetic polymorphism of αS1- casein gene on qualitative and quantitative bovine milk traits. Anniversary Scientific Session “110 years NDSRVMI”. 8-9 November. Sofia. Bulgaria.
  9. Teofanova D., Hristov P., Yoveva A., Radoslavov G. 2011. Native and recombinant fatty acid binding protein 3 from Fasciola hepatica as a potential antigen. Anniversary Molecular Biology Conference “50 years Roumen Tsanev Institute of Molecular Biology”. 6-7 October. Sofia. Bulgaria.
  10. Hristov P., Teofanova D., Mehandzhiyski I., Yoveva A., Radoslavov G. 2011. Genotyping of endemic for Rhodopy mountain Shorthorn Rhodopean cow breed. Anniversary Molecular Biology Conference “50 years Roumen Tsanev Institute of Molecular Biology”. 6-7 October. Sofia. Bulgaria.
  11. Teofanova D., Yoveva A., Hristov P., Radoslavov G. 2011. First reported natural histidine tailed protein family (PCHTP family). Anniversary Molecular Biology Conference “50 years Roumen Tsanev Institute of Molecular Biology”. 6-7 October. Sofia. Bulgaria.
  12. Hristov P., Teofanova D., Mehandzhiyski I., Yoveva A., Radoslavov G. 2011. Selection of diary cows with respect to kappa-casein gene polymorphism. XIV Scientific Conference with international participation “Ecological Problems of Mountain Agriculture”. 26-27 May. Troyan. Bulgaria.
  13. Teofanova D., Radoslavov G., Hristov P., Walker S., Trudget A., Kanzoura V., Theodoropoulos G., Bankov I. 2010. Definition of liver fluke population groups by DNA polymorphisms. BSP Spring Meeting. Cardiff, Wales, UK.
  14. Hristov P., Radoslavov G., Jordanova R., Teofanova D., Liebau E., Bankov I. 2010. New metalloprotein of parasitic nematodes from the genus Trichinella. BSP Spring Meeting. Cardiff, Wales, UK.
  15. Teofanova D., Radoslavov G., Hristov P., Walker S., Trudget A., Kanzoura V., Theodoropoulos G., Bankov I. 2009. Genotyping of liver fluke populations in Eastern Europe. VIII National Conference of Parasitology. Varna, 22-25 September.
  16. Radoslavov G., Jordanova R., Teofanova D., Hristov P., Liebau E., Bankov I. 2009. Investigation of new Poly-Cys and His-Tailed Protein (PCHT) of parasitic nematodes from the genus Trichinella. VIII National Conference of Parasitology. Varna, 22-25 September.
  17. Nanev V., Radoslavov G., Teofanova D., Hrusanov D., Radev V. 2009. The PCR-RFLP method used for determination of female specimens of the genus Haemonchus. VIII National Conference of Parasitology. Varna, 22-25 September.
  18. Hristov P., Teofanova D., Radoslavov G. 2009. Impact of genetic polymorphism of the beta-lactoglobulin locus on milk productivity and quality features of cow's milk. 2nd Spring Seminar of PhD students and young scientists from BAS "Interdisciplinary Chemistry", 24-26 April 2009, Sofia.
  19. Teofanova D., Radoslavov G., Bankov I. 2008. Molecular-biology and biochemical methods. XI winter seminar of interdisciplinary physics. Sofia. Bulgaria. 12-14 December.
  20. Teofanova D., Radoslavov G., Hristov P. 2008. Usage of biological markers for selection and breeding of dairy cattle. XI winter seminar of interdisciplinary physics. Sofia. Bulgaria. 12-14 December.
  21. Hristov P., Teofanova D., Zlatarev S., Radoslavov G., Mehandzhiyski I. 2008. The influence of milk proteins genetic polymorphism on milk production traits in cows of the Bulgarian Rhodopean cattle. Anniversary Scientific Conference, 25-26 September, Smolyan, 51-58.
  22. Radoslavov G., Teofanova D., Liebau E., Bankov I. 2008. Investigation of lipid binding proteins of parasitic helmintes from the genus Trichinella and Fasciola . Xth Еuropean Мulticolloquium of Parasitology. Paris. 24-28 August.
  23. Radoslavov G., Jordanova R., Ivanova T., Teofanova D., Liebau E., Bankov I. 2007. Investigation of native and recombinant fatty acid binding protein 3 (FABP 3) from the liver fluke Fasciola hepatica as a potential antigen. Sofia School of Protein Science. 3-5 October. Sofia. Bulgaria.
  24. Radoslavov G., Jordanova R., Ivanova T., Teofanova D., Liebau E., Bankov I. 2007. Comparative investigation of lipid binding protein of parasitic nematodes from the genus Trichinella. Sofia School of Protein Science. 3-5 October. Sofia. Bulgaria.
  25. Radoslavov G., Jordanova R., Ivanova T., Teofanova D., Liebau E., Bankov I. 2007. Comparative investigation of lipid binding protein of parasitic nematodes from the genus Trichinella. Joint Malaria and Spring Meeting of The Irish Society for Parasitology and The British Society for Parasitology at the Queens University, Belfast