CV
| Daniela Tsvetanova Tsekova Email: DTsekova@chem.uni-sofia.bg Phone: + 359 2 8161347 Fax: + 359 2 9625438 Sofia University „St. Kliment Ohridski” Faculty of Chemistry and Pharmacy 1164 Sofia, 1 James Bourchier Blivd. |
Education
- M.Sc. – specialty - Chemistry, specialization – Inorganic and Analytical Chemistry, Sofia University „St. Kliment Ohridski”
- Ph.D – specialty – Analytical chemistry, University of Sofia „St. Kliment Ohridski”
Professional Experience
- Assistant Professor, Sofia University „St. Kliment Ohridski” 2000 - 2008
- Senior Assistant Professor, Sofia University „St. Kliment Ohridski” 2008
- Chief Assistant Professor, Sofia University „St. Kliment Ohridski” since 2008
Research Interests
- Coordination chemistry, Complexes of platinum, palladium and gold, Complexes with cytotoxic activity
Selected Publications (max 5)
- G. Gencheva, D. Tsekova, G. Gochev, D. Mehandjiev, P. R. Bontchev: “Monomeric Au(II) complex with hematoporphyrin IX”, Inorg. Chem. Commun., 6 (2003) 325. Article Number: PII S1387-7003(02)00747-5 doi: 10.1016/S1387-7003(02)00747-5
- G. Gencheva, D. Tsekova, G. Gochev, G. Momekov, G. Tyuliev, V. Skumryev, M. Karaivanova, P. R. Bontchev, Synthesis, structural characterization and cytotoxic activity of novel paramagnetic platinum hematoporphyrin IX complexes – potent antitumour agents, Metal-Based Drugs, Volume 2007 (2007), Article ID 67 376, 13 pages. doi: 10.1155/2007/67376.
- G. Momekov, M. Karaivanova, I. Ugrinova, E. Pasheva, G. Gencheva, D. Tsekova, S. Arpadjan, P. R. Bontchev: In vitro pharmacological study of monomeric platinum(III) hematoporphyrin IX complexes, Invest. New Drugs, (2010), 10 pages. doi: 10.1007/s10637-010-9412-8.
- D. Tsekova, P. Gorolomova, G. Gochev, V. Skuryev, G. Momekov, D. Momekova, G. Gencheva: Synthesis, structure and in vitro cytotoxic studies on novel paramagnetic palladium(III) complexes with hematoporphyrin IX, Journal of Inorganic Biochemistry, 124 (2013) 54-62. doi: 10.1016/j.jinorgbio.2013.03.012
- G. Momekov, I. Ugrinova, E. Pasheva, D. Tsekova, G. Gencheva: Cellular Pharmacology of Palladinum(III) Hematoporphyrin IX Complexes: Solution Stability, Antineoplastic and Apoptogenic Activity, DNA Binding, and Processing of DNA-Adducts. International Journal of Molecular Science, 19, 2018, 2451, 21 pages; doi: 10.3390/ijms19082451
Textbooks and Teaching Aids
- G. Pekov, D. Tsekova, G. Gencheva: Problems in Analytical Chemistry. Processes and their application in chemical methods for analysis, Sofia University “St. Kliment Ohridski” Publishing House, Sofia, 2016. ISBN 978-954-07-4100-0
Project Activity – (Research Projects in the last 5 years)
- “Rational Design of New Metal-Based Antitumor Agents, National Science Fund, Ministry of Education and Science, 2016–, Assoc. Prof. PhD G. Gencheva.
Teaching Activity
Period from - to | Discipline | Specialty |
1999/2000 - | Practice at „Analytical Chemistry” | specialty (full time): Chemistry (180 hours); Computer Chemistry (120 hours); ECO Chemistry (120 hours); Nuclear Chemistry (75 hours); Chemistry in engineering. Contemporary materials (75 hours); Biology (45 hours); Molecular Biology (45 hours); Ecology and Environmental Protection (45 hours); Pharmacy (100 hours) specialty (part time): Chemistry (75+40 hours); Chemistry and English (45 hours); Biology (23ours); Ecology and Environmental Protection (23hours) |
2011/2012 - | Practice at „Instrumental methods - II part” | specialty (full time): Chemistry (15 hours); ECO Chemistry (15 часа); Nuclear Chemistry (15hours); Chemistry and Informatics (6 часа) |
2011/2012 - | Practice at „Coordination compounds in Analytical Chemistry” | specialty (part time): Chemistry (10 hours) |
2015/2016 and 2016/2017 | Lectures at „Analytical Chemistry” | specialty (full time): Chemistry (30 hours); Computer Chemistry; ECO Chemistry; Chemistry and Informatics (30 hours) |
2017/2018 - | Lectures at „Analytical Chemistry” | specialty (full time): Chemistry and English (30 hours); Bio-management and sustainable development (30 hours); specialty (part time): Chemistry (25+10 hours); |
External Scientific Service Activities
Reviewer of Manuscripts for:
- Bulg. Chem. Commun. (2)