| Assist. Prof. Dr. Nevena Petkova Sofia University “St. Kl. Ohridski”, Faculty of Chemistry and pharmacy Department of Organic chemistry and pharmacognosy, room 236 1 J. Baurchier blvd, 1164, Sofia, Bulgaria Phone: +359 2 8161 384 e-mail: nipetkova@chem.uni-sofia.bg |
Education and academic degrees
2007 – PhD in Organic chemistry, Sofia University “St. Kl. Ohridski”
2000 – M.Sc. in chemistry, Sofia University “St. Kl. Ohridski”
Professional experience
2008 – Assistant Professor, Department of Organic chemistry and pharmacognosy, Sofia University “St. Kl. Ohridski”
2004 – 2008 Researcher, Department of Organic chemistry, Sofia University “St. Kl. Ohridski”
Additional academic positions, awards and guest professorships:
2007 - Award of the Union of Bulgarian Scientist for Excellent PhD Thesis for 2007
Fellowships and research visits abroad
September 2011 – September 2013, 3B´s Research Group - Biomaterials, Biodegradables and Biomimetics, Department of Polymer Engineering, University of Minho
March 2014 - Central Research Laboratory, Department of Chemistry, and University of Oxford, England
July –August 2014 - Central Research Laboratory, Department of Chemistry, and University of Oxford, England
January – February 2015 - Central Research Laboratory, Department of Chemistry, and University of Oxford, England
Research interests
Organic synthesis. Organophosphorus compounds
Design and synthesis of methylenebisphosphonic acid derivatives containing heterocyclic groups to the central carbon atom. Preparation of salts of substituted methylenebisphosphonic acid as potential active substances
Synthesis of new phosphorous-containing coumarin derivatives – Synthetic methods for preparation of phosphorous-containing coumarins via Knoevenagel, Arbuzov and Perkow reactions
Reactions of conjugated nucleophilic addition. Developed a novel one-pot tandem reaction for hydrogenation / acylation of 3-substituted coumarins
Bioorthogonal chemical reactions
-Synthesis of high reactive and selective strained cyclooctynes for copper-free click reaction
-Preparation of unnatural monosaccharides bearing chemical reporters
NMR laboratory at FCP
-Structure elucidation of newly synthesized organic molecules in solution and solid state using one and two dimensional NMR techniques
-New NMR techniques in Organic Chemistry
Selected publications (up to 5)
A. I. Koleva, N. I. Petkova, R. D. Nikolova Ultrasound-assisted Conjugate Addition of Organometallic Reagents to 3-Diethylphosphonocoumarin Synlett 2016, 27, 2676.
N. I. Petkova, R. D. Nikolova, K. L. Kostov, T. Mineva, G. N. Vayssilov Theoretical and experimental local reactivity parameters of 3-substituted coumarin derivatives, J.Phys.Chem. A, 2014, 118 (46), 11062.
E. D. Ilieva, N. I. Petkova, R. D. Nikolova Ring Opening Reactions of 3-Phosphonocoumarin under Michael Reaction Conditions, Phosphorus, Sulfur and Silicon and the Related Elements, 2012, 187, 39.
N. I. Petkova, R. D. Nikolova, A. G. Bojilova, N. A. Rodios, J. Kopf Synthesis of heterocyclic methylenebisphosphonates by 1,3-dipolar cycloaddition of ethyl diazoacetate to 1,2-benzoxaphosphorin-3-phosphonates, Tetrahedron, 2009, 65, 1639.
N. I. Petkova, R. D. Nikolova, A. G. Bojilova, N. A. Rodios, C. P. Raptopoulou Hydrogenation / Regioselective C-acylation reaction of diethyl coumarin-3-phosphonate with NaBH4 / acid anhydrides. A new one pot tandem reaction, Synth. Commun., 2006, 36, 509.
Projects (last 5 years)
2009 – 2013, Find and Bind: FP7-NMP-2008-SMALL-2 “Mastering sweet cell-instructive biosystems by copycat nano-interaction of cells with natural surfaces for biotechnological applications” – team member
2012 – 2015, POLARIS: “Unlocking the research potential of 3Bs Group, University of Minho, in Nanomedicine field to strengthen its competitive position at the European level” – team member
2015, Sofia University “St. Kl. Ohridski” № 160 / 17.04.2015 Development and popularization of Nuclear Magnetic Resonance laboratory at Faculty of Chemistry and Pharmacy at Sofia University – team member
2016, Sofia University “St. Kl. Ohridski” № 157 / 12.04.2016 NMR - laboratory at Faculty of Chemistry and Pharmacy – technical support and developing investigations – team member
2017, Sofia University “St. Kl. Ohridski” Technical support and developing investigations at the NMR - laboratory at Faculty of Chemistry and Pharmacy – team member.
Other professional activities
Editorial board memberships:
Referee of publications in: Current Organic Synthesis, Turkish Journal of Chemistry
Co-authorships in books or chapters in books:
Textbooks and manuals:
Teaching
Lectures:
Organic chemistry II – Bachelor programme Biology and Chemistry, 45 h
Practicums:
Seminars and practical exercises in Organic chemistry I and II – all bachelor programmes in FCP and FB