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vyara

Vyara Velcheva

Email: ahvnv@chem.uni-sofia.bg

Phone: + 359 2 8161345

Sofia University „St. Kliment Ohridski”

Faculty of Chemistry and Pharmacy

1164 Sofia, 1 James Bourchier Blvd.

Education

  • Ph.D – Chemical Sciences (Analytical chemistry), Sofia University "St. Kliment Ohridski", 2023
  • M. Sc. – “Medicinal Chemistry”, Sofia University “St. Kliment Ohridski”, 2014
  • B. Sc. – “Computer Chemistry”, Sofia University “St. Kliment Ohridski”, 2012

Professional Experience

  • Head Assistant Professor (Analytical Chemistry, Sofia University "St. Kliment Ohridski" (15. 2024 - present)
  • Assistant Professor (Analytical chemistry), Sofia University "St. Kliment Ohridski" (11. 2017 - present)
  • Assistant Professor (Analytical chemistry), Sofia University "St. Kliment Ohridski" (10.2015 – 07.2016)

Specializations

  • 2-weeks specialization, project “MODERN-A: Modernization in partnership through digitalization of the Academic ecosystem” as part of activity short-term specialisation at associated partner institutions BG05M2OP001-2.016-0018, University of Alicante, Alicante, Spain, 02.12-15.12.2023
  • 3th Summer School of Bioinorganic Medicinal Chemistry, 2017, Cagliari, Sardegna, Italy, 28.08-02.09.2017
  • 3-weeks spetialization in Saarland University, Saarbrucken, Germany; 05-22.12.2016
  • International School on Introduction in the Rietveld structure refinement, Bulgarian Academy of Sciences, Sofia, Bulgaria, 28.09-03.10.2015
  • International School on Fundamental Chrystallography: Introduction on the international tables for Chrystallography, Sofia-Gyulechitsa, Bulgaria, 30.09-05.10.2013.
  • Second Balkan School on Fundamental Crystallography and Workshop on Magnetic Symmetry, Energy Institute, Istanbul Technical University Campus, Istanbul, Turkey, 13-19.07.15

Research Interests

  • coordination compounds, anticancer activity, IR-spectroscopy, UV-VIS-spectroscopy, NMR-spectroscopy, X-ray analysis

Publications

  • Velcheva, Vyara, Hegetschweiler, Kaspar and Gencheva, Galina. "Crystal structure of all-cis-2,4,6-trihydroxycyclohexane- 1,3,5-triaminium chloride sulfate, C6H18ClN3O7S" Zeitschrift für Kristallographie - New Crystal Structures, vol. 236, no. 6, 2021, pp. 1319-1321. https://doi.org/10.1515/ncrs-2021-0324
  • Velcheva, V.; Hegetschweiler, K.; Momekov, G.; Ivanova, S.; Ugrinov, A.; Morgenstern, B.; Gencheva, G. Platinum(IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic Drug Candidates. Pharmaceutics 2022, 14 (10). DOI: 10.3390/pharmaceutics14102057

Project Activity

  • Scientific Project “Synthesis, Structure and properties of Pt(IV) complexes with mono-, di- and tricarbamate derivatives of the ligand 2,4,6-triaminocyclohexane-1,3,5-triol (taci), 2024, NSF-SU, 80-10-167/2024
  • Project for Financial Support for Scientific Publication “ „Platinum(IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic DrugCandidates. Pharmaceutics 2022, 14, 2057“, NSF - SU, 80-10-99/2022
  • Rational Design of New Metal-Based Antitumor Agents”, National Science Fund, Ministry of Education and Science, 2016-, Head of Project- assoc. prof. PhD G. Gencheva.

Teaching Activity

Period from - to Discipline Specialty
10.2015- 02.2016 Analytical Chemistry and Methods for Analysis Biology and Chemistry, Ecology and Environmental Protection
02.2016-05.2016 Analytical Chemistry I, II Biotechnology, Biology, Molecular Biology
02.2016-05.2016 Instrumental Methods for Analysis II Nuclear Chemistry, ECO chemistry, Chemistry
02.2018-present Instrumental Methods for Analysis II Nuclear Chemistry, ECO chemistry, Chemistry
02.2018-present Analytical Chemistry and Methods for Analysis Biotechnology, Biology, Molecular Biology
10.2018-present Analytical Chemistry I, II Computer Chemistry, ECO chemistry
10.2019- present Analytical Chemistry I, II Chemistry
03.2024 Analytival Chemistry and Instrumenthal Methods II

Chemistry and English

Chemistry and Informatics

Biology and Chenistry

Conferences

  1. Vyara Velcheva, Kaspar Hegetschweiler, Angel Ugrinov, Georgi Momekov and Galina Gencheva, Platinum(IV) complexes of the 1,3,5-triamino-1,3,5-trideoxy-cis-inositol- synthesis, structure and antiproliferative properties, Eleventh International Conference on Radiation, Natural Sciences, Medicine, Engineering, Technology and Ecology, Herceg Novi, Montenegro, 19 – 23.06.23, p. 135.
  2. Vyara N. Velcheva, Georgi T. Momekov, Angel G. Ugrinov, Nikola T. Burdjiev and Galina G. Gencheva, Studies on the Solution Behavior of Novel Platinum(IV) Complexes with a N,O- Chelating Ligand Designed as Potential Cytotoxic Agents, 2nd International Conference on Medicinal Chemistry and Drug Design, Renaissance Barcelona Fira Hotel, Barcelona, Spain, 19 - 20.08.19, p 42.

External Scientific Activities

  • Member of the National commission for organizing the National Olympiad in Chemistry and Environmental Protection - from 2017 to the present