CV
Galina Gencheva Email: ggencheva@chem.uni-sofia.bg Тел.: + 359 2 8161 208/347/394 Факс: + 359 2 9625438 Sofia University „St. Kliment Ohridski” Faculty of Chemistry and Pharmacy 1164 Sofia, 1 James Bourchier Blivd. |
Education
- M. Sc. – Chemistry, Inorganic and Analytical Chemistry, University of Sofia, “St. Kliment Ohridski”, 1986
- Ph.D - Analytical Chemistry, University of Sofia, “St. Kliment Ohridski”, 1993
Professional Experience
- Professor, Analytical Chemistry, Sofia University „St. Kliment Ohridski”, 2004 - 2024
- Associate Professor, Analytical Chemistry, Sofia University „St. Kliment Ohridski”, 2004 - 2024 .
- Assistant Professor, Analytical Chemistry, Sofia University „St. Kliment Ohridski”, 1997 – 2004;
- Assistant in Analytical Chemistry and in Inorganic Chemistry, Sofia University „St. Kliment Ohridski”, 1992 - 1997;
Specializations and Visiting Researcher at:
- Prof. Dr. Dr.h.c. Bernt Krebs, Institut fuer Anorganische und Analytische Chemie, Westfaelische Wilhelms-Universitaet Muenster, Muenster, Germany
- Prof. Dr. Kaspar Hegetschweiler, Univerisitaet des Saarlandes, Saarbruecken, Germany
- Department of Chemistry and Biochemistry, North Dakota State University, United States – Angel Ugrinov, PhD
Research Interests
- Instrumental methods and their application for molecular structure determination and quantitative analysis: Infrared and Raman Spectroscopy, Ultraviolet and Visible Absorption Spectroscopy, Electro Paramagnetic Resonance, Nuclear Magnetic Resonance, Magnetic Measurements, Single Crystal X-Ray Diffraction, Electroanalytical Methods.
- Synthesis, structure, physicochemical properties and application of coordination compounds designed as new materials and antiproliferative drugs.
Selected Publications
- V. Velcheva, K. Hegetschweiler, G. Momekov, S. Ivanova, A. Ugrinov, B. Morgenstern, G. Gencheva: Platinum(IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic Drug Candidates, Pharmaceutics, 14, 2057, 2022. https://doi.org/10.3390/pharmaceutics14102057
- G. Momekov, I. Ugrinova, E. Pasheva, D. Tsekova, G. Gencheva “Cellular Pharmacology of Palladinum(III) Hematoporphyrin IX Complexes: Solution Stability, Antineoplastic and Apoptogenic Activity, DNA Binding, and Processing of DNA-Adducts”, Int. J. Mol. Sci., 19, 2451, 2018. https://doi.org/10.3390/ijms19082451.
- D. Tsekova, P. Gorolomova, G. Gochev, V. Skuryev, G. Momekov, D. Momekova, G. Gencheva: Synthesis, structure and in vitro cytotoxic studies on novel paramagnetic palladium(III) complexes with hematoporphyrin IX, Journal of Inorganic Biochemistry, 124, 54, 2013. https://doi.org/10.1016/j.jinorgbio.2013.03.012
- P. Gorolomova, R. Petrova, B. Shivachev, V. Ilieva, D. Tsekova, T. Tosheva, E. Tashev, S. Varbanov, G. Gencheva: Theoretical and experimental studies on the coordination ability of 1,4-bis(dimethylphosphinylmethyleneoxy) benzene, Bulgarian Chemical Communications 43, 244, 2011.
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M. Georgieva, Z. Gospodinova, M. Keremidarska-Markova, T. Kamenska, G. Gencheva, N. Krasteva: PEGylated nanographene oxide in combination with near-infrared laser
irradiation as a smart nanocarrier in colon cancer targeted therapy, Pharmaceutics, 13, 424, 2021. https://doi.орг/10.3390/pharmaceutics13030424.
Project Activity – (Research Projects in the last 5 years)
- National Science Fund, DN09/2016-2020: Rational Design of New Metal-Based Antitumor Agents.
- Sofia University “St. Kliment Ohridski”, Competition for Publication, 80-10-99/2022, Platinum (IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic Drug Candidates. (Pharmaceutics 2022, 14, 2057). Sofia University “St. Kliment Ohridski”
- Sofia University “St. Kliment Ohridski”, Thematic Competition, 80-10-167/2024, Synthesis and structure of complexes of Pt(IV) with mono-, di- and tricarbamate forms of the ligand 2,4,6-triaminocyclohexane-1,3,5-triol (taci).
- European Union-Next Generation EU. National Recovery and Resilience Plan of the Republic of Bulgaria, No.70-123-662/2024
Teaching Activity
Period from - to | Discipline | Specialty |
2009 - | Instrumental Methods II | Bachelor’s Degree Programmes: Chemistry, ECO Chemistry, Nuclear Chemistry, Engineering and Modern materials, Chemistry and Informatics |
2009 - | Vibrational Spectroscopy – Methods and Application | Bachelor’s Degree Programmes: (all) |
2009 - | Modern Methods in Molecular Spectroscopy | Master’s Degree Programme: Modern Spectral and Chromatographic Analytical Methods |
2010 - | Infrared and Raman Spectroscopy | Master’s Degree Programmes |
2010 - | Electron spectroscopy (UV/VIS, fluorescence) | Master’s Degree Programmes |
2021 - | Modern applications of molecular spectroscopy in chemical analysis | Master’s Degree Programme: Smart Analytics |
2006 - | Electroanalytical Methods | Master’s and Bachelor’s Degree Programmes |
2003 - | Coordination Compounds in Analytical Chemistry | Bachelor’s Degree Programmes: Chemistry, Analytical Chemistry |
2005 – 2009 | Analytical Chemistry I & II | Bachelor’s Degree Programmes: Eco Chemistry, Computational Chemistry, Biology, Microbiology |
2022 - | Analytical Chemistry and Instrumental Methods | Chemistry and Informatics, Chemistry and English, Biology and Chemistry |
External Scientific Service Activities
- Member of Editorial Board of Bulgarian Chemical Communication – Special Issue of 2015, dedicated to Vth National Crstallographic Symposium, 2014, Sofia.
- Member of “Bulgarian Crystallographic Association” since 2010 - presentReviewer of Manuscripts for:
Reviewer of Manuscripts for: European Journal of Medicinal Chemistry; Asian Chemistry Letters, Bulgarian Chemical Communications, Chemistry, Anti-Cancer Agents in Medicinal Chemistry, Pharmaceutics, Int. J. Mol. Sci., Crystal
Textbooks and Teaching Aids
- G. Pekov, D. Tsekova, G. Gencheva: Problems in Analytical Chemistry. Processes and their Application in Chemical Methods for Analysis, 2016.
- E. Mladenova, I. Karadjova, G. Gencheva, D. Tsekova, N. Burdjiev, G. Pekov, N. Varbanova, N. Stamenov: Chemistry and environmental protection: Methods for control and analysis of substances, 12th grade, 2021.