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CV

Galina Gencheva

Email: ggencheva@chem.uni-sofia.bg

Тел.: + 359 2 8161 208/347/394

Факс: + 359 2 9625438

Sofia University „St. Kliment Ohridski”

Faculty of Chemistry and Pharmacy

1164 Sofia, 1 James Bourchier Blivd.

Education

  • M. Sc. – Chemistry, Inorganic and Analytical Chemistry, University of Sofia, “St. Kliment Ohridski”, 1986
  • Ph.D - Analytical Chemistry, University of Sofia, “St. Kliment Ohridski”, 1993

Professional Experience

  • Professor, Analytical Chemistry, Sofia University „St. Kliment Ohridski”, 2004 - 2024
  • Associate Professor, Analytical Chemistry, Sofia University „St. Kliment Ohridski”, 2004 - 2024 .
  • Assistant Professor, Analytical Chemistry, Sofia University „St. Kliment Ohridski”, 1997 – 2004;
  • Assistant in Analytical Chemistry and in Inorganic Chemistry, Sofia University „St. Kliment Ohridski”, 1992 - 1997;

Specializations and Visiting Researcher at:

  • Prof. Dr. Dr.h.c. Bernt Krebs, Institut fuer Anorganische und Analytische Chemie, Westfaelische Wilhelms-Universitaet Muenster, Muenster, Germany
  • Prof. Dr. Kaspar Hegetschweiler, Univerisitaet des Saarlandes, Saarbruecken, Germany
  • Department of Chemistry and Biochemistry, North Dakota State University, United States – Angel Ugrinov, PhD

Research Interests

  • Instrumental methods and their application for molecular structure determination and quantitative analysis: Infrared and Raman Spectroscopy, Ultraviolet and Visible Absorption Spectroscopy, Electro Paramagnetic Resonance, Nuclear Magnetic Resonance, Magnetic Measurements, Single Crystal X-Ray Diffraction, Electroanalytical Methods.
  • Synthesis, structure, physicochemical properties and application of coordination compounds designed as new materials and antiproliferative drugs.

Selected Publications

  1. V. Velcheva, K. Hegetschweiler, G. Momekov, S. Ivanova, A. Ugrinov, B. Morgenstern, G. Gencheva: Platinum(IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic Drug Candidates, Pharmaceutics, 14, 2057, 2022. https://doi.org/10.3390/pharmaceutics14102057
  2. G. Momekov, I. Ugrinova, E. Pasheva, D. Tsekova, G. Gencheva “Cellular Pharmacology of Palladinum(III) Hematoporphyrin IX Complexes: Solution Stability, Antineoplastic and Apoptogenic Activity, DNA Binding, and Processing of DNA-Adducts”, Int. J. Mol. Sci., 19, 2451, 2018. https://doi.org/10.3390/ijms19082451.
  3. D. Tsekova, P. Gorolomova, G. Gochev, V. Skuryev, G. Momekov, D. Momekova, G. Gencheva: Synthesis, structure and in vitro cytotoxic studies on novel paramagnetic palladium(III) complexes with hematoporphyrin IX, Journal of Inorganic Biochemistry, 124, 54, 2013. https://doi.org/10.1016/j.jinorgbio.2013.03.012
  4. P. Gorolomova, R. Petrova, B. Shivachev, V. Ilieva, D. Tsekova, T. Tosheva, E. Tashev, S. Varbanov, G. Gencheva: Theoretical and experimental studies on the coordination ability of 1,4-bis(dimethylphosphinylmethyleneoxy) benzene, Bulgarian Chemical Communications 43, 244, 2011.
  5. M. Georgieva, Z. Gospodinova, M. Keremidarska-Markova, T. Kamenska, G. Gencheva, N. Krasteva: PEGylated nanographene oxide in combination with near-infrared laser
    irradiation as a smart nanocarrier in colon cancer targeted therapy, Pharmaceutics, 13, 424, 2021. https://doi.орг/10.3390/pharmaceutics13030424.

List of Publications

Project Activity – (Research Projects in the last 5 years)

  • National Science Fund, DN09/2016-2020: Rational Design of New Metal-Based Antitumor Agents.
  • Sofia University “St. Kliment Ohridski”, Competition for Publication, 80-10-99/2022, Platinum (IV) Complexes of the 1,3,5-Triamino Analogue of the Biomolecule Cis-Inositol Designed as Innovative Antineoplastic Drug Candidates. (Pharmaceutics 2022, 14, 2057). Sofia University “St. Kliment Ohridski”
  • Sofia University “St. Kliment Ohridski”, Thematic Competition, 80-10-167/2024, Synthesis and structure of complexes of Pt(IV) with mono-, di- and tricarbamate forms of the ligand 2,4,6-triaminocyclohexane-1,3,5-triol (taci).
  • European Union-Next Generation EU. National Recovery and Resilience Plan of the Republic of Bulgaria, No.70-123-662/2024

Teaching Activity

Period from - to Discipline Specialty
2009 - Instrumental Methods II Bachelor’s Degree Programmes: Chemistry, ECO Chemistry, Nuclear Chemistry, Engineering and Modern materials, Chemistry and Informatics
2009 - Vibrational Spectroscopy – Methods and Application Bachelor’s Degree Programmes: (all)
2009 - Modern Methods in Molecular Spectroscopy Master’s Degree Programme: Modern Spectral and Chromatographic Analytical Methods
2010 - Infrared and Raman Spectroscopy Master’s Degree Programmes
2010 - Electron spectroscopy (UV/VIS, fluorescence) Master’s Degree Programmes
2021 - Modern applications of molecular spectroscopy in chemical analysis Master’s Degree Programme: Smart Analytics
2006 - Electroanalytical Methods Master’s and Bachelor’s Degree Programmes
2003 - Coordination Compounds in Analytical Chemistry Bachelor’s Degree Programmes: Chemistry, Analytical Chemistry
2005 – 2009 Analytical Chemistry I & II Bachelor’s Degree Programmes: Eco Chemistry, Computational Chemistry, Biology, Microbiology
2022 - Analytical Chemistry and Instrumental Methods Chemistry and Informatics, Chemistry and English, Biology and Chemistry

External Scientific Service Activities

- Member of Editorial Board of Bulgarian Chemical Communication – Special Issue of 2015, dedicated to Vth National Crstallographic Symposium, 2014, Sofia.

- Member of “Bulgarian Crystallographic Association” since 2010 - presentReviewer of Manuscripts for:

Reviewer of Manuscripts for: European Journal of Medicinal Chemistry; Asian Chemistry Letters, Bulgarian Chemical Communications, Chemistry, Anti-Cancer Agents in Medicinal Chemistry, Pharmaceutics, Int. J. Mol. Sci., Crystal

Textbooks and Teaching Aids

  • G. Pekov, D. Tsekova, G. Gencheva: Problems in Analytical Chemistry. Processes and their Application in Chemical Methods for Analysis, 2016.
  • E. Mladenova, I. Karadjova, G. Gencheva, D. Tsekova, N. Burdjiev, G. Pekov, N. Varbanova, N. Stamenov: Chemistry and environmental protection: Methods for control and analysis of substances, 12th grade, 2021.